I've been on a trans-pacific flight to Asia.... Been there.
Bring a laptop and charger (some airlines have wifi)
if multiple people in group: cut a risk game board into four and have people split it between them, then congregate in the back of the 777 for a long game. Settlers of kattan is an awesome pick too.
Cards... Lots of cards (15 deck shitty boots game anyone?)
Someone to suck face with
Lots of porn and retreat to an excriment facility
Lots of zannex... Lol, or ambien
Throwing magnets (if you like to annoy people)
An iPod filled to the brim, or with multiplayer Bluetooth/wifi games
The list goes on...
I was lucky, I had my gf with me... I can honestly say the mile high and multiple 3rd world club patches are on my sleeve.