First off technically air is not pulled in. its pushed from a higher pressure to a lower... Understand that before you comment.
A pent roof chamber provides little shrouding, therefore bigger valves should not have a problem with shrouding, regardless of lift.
If Boosted with a Turbocharger, you have far more exhaust pressure and volume to release into a restriction, if the turbo is efficient and has low back pressure all is well, but is not always the case. If you have a system where you have alot of backpressure, more exhaust flow will benefit.
Also, if the chamber is not entirely purged of exhaust gasses, your wasting energy re-compressing heated inert exhaust gasses from the previous cycle.